ActoFactor™ Recombinant Human CD2 molecule
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Cat.No.
CSC-CTK0298
Description
CD2 (25-209 a.a.) which is also known as E-rosette receptor, T11 and lymphocytefunction antigen-2 (LFA-2) is expressed on T cells, thymocytes, and a subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
Species
                                Human
                            Product Overview
                                Human CD2 expressed in E.coli
                            Molecular Mass
                                46 kDa
                            Size
                                CAT# CSC-CTK0298-2    2 μg; CAT# CSC-CTK0298-10 (10 μg)
                            Expression System
                                E.coli
                            Purity
                                N/A
                            Activity
                                N/A
                            Endotoxin Level
                                N/A
                            Formulation
                                Sterile-filtered, clear soultion. Recombinant protein at 100 μg/ml in 50 mM Tris-acetate (pH 7.5), 1 mM EDTA and 20% glycerol.
                            Reconstitution
                                N/A
                            Storage & Stability
                                Please Note: Always centrifuge product briefly before opening vial. Store vial at –20°C to –80°C. When stored at the recommended temperature, this protein is stable for 12 months. Avoid repeated freeze-thaw cycles.
                            Citation Guidance
                        
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