In Situ Detection of Virus
Viruses that infected cells elicit specific changes to normal cell functions which serve to divert energy and resources for viral replication. Many aspects of host cell function are commandeered by viruses. Moreover, viruses engineer specific membrane organelles or tag on to mobile vesicles and motor proteins to target regions of the cell.
Direct detection of viral RNA or DNA in human or other animal cells by in situ hybridization (ISH) is a powerful tool to establish the etiology and pathogenesis of viral diseases. And ISH represents an important tool, because a correlation between virus and lesion distribution can be achieved. This might provide a strong indication for a possibel pathogneic relation between the pathogen in question and observed tissue pre-selection of potentially pathogenic viruses, the ISH detection rate is an important factor for generating the most effective protocol. With many years of experience and in-depth knowledge in ISH, Creative Bioarray offers the In Situ detection of Virus.
Fig 1. Detection of different viruses in cells by ISH
Applications
- In Situ detect the distribution of viruses in tumor cells or tissues
- Identify different kinds of viruses
Features
- Accurate-In Situ Detection Service-Custom design your probe
- Value – We focus on the quality of our service and all supported by competitive pricing
- Efficiency – We are able to provide the fastest turnaround time of any supplier in the industry
Creative Bioarray offers In Situ detection of Virus for your scientific research as follows:
- Probe design
- Probe synthesis
- FISH/ISH on samples
- Imaging
- Data analysis
Quotation and ordering
Our customer service representatives are available 24hr a day! We thank you for choosing Creative Bioarray at your preferred In Situ detection of Virus Service.
References
- Pfankuche,; et al. "Comparison of different in situ hybridization techniques for the detection of various RNA and DNA viruses." Viruses 10.7 (2018): 384.
- Chou, ; et al. "Colocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis." PLoS pathogens 9.5 (2013): e1003358.
- Sur, ; et al. "In vivo detection of porcine reproductive and respiratory syndrome virus RNA by in situ hybridization at different times postinfection." Journal of clinical microbiology 34.9 (1996): 2280-2286.
