Brain Organoid Differentiation Service from iPSC

While induced pluripotent stem cells (iPSCs) have replaced the ethically questionable human embryonic stem cells, iPSC-based neuronal differentiation studies remain descriptive at the cellular level but fail to adequately provide the details that could be derived from a complex, 3D human brain tissue. Brain organoids have emerged as an excellent model for investigating brain development and the mechanisms of related diseases.

Creative Bioarray developed a protocol that is able to differentiate brain organoids from induced Pluripotent Stem Cells(iPSCs). We also provide characterization of iPSC-derived organoids using immunocytochemistry and multi-electrode array (MEA).

iPSC-derived brain organoids can be used for

  • Exploring mechanisms for neurological disorders
  • Drug screening
  • Modeling brain disorders
  • Development of organ-chips

iPSC-derived brain organoids

We provide various types of brain organoids:

  • Microglia-enriched brain organoid
  • Oligodendrocytes brain organoid
  • Blood-vessel-enriched brain organoid

The brain organoids we deliver are a mixture of various neuronal cells, and the mixing ratio can be adjusted according to customer requirements.

Phase contrast images taken after differentiation, showing the morphological changes occurred.Figure 1. Phase contrast images taken after differentiation, showing the morphological changes occurred.

Differentiation of different types of brain organoids.Figure 2. Differentiation of different types of brain organoids.

Creative Bioarray also provides iPSC-derived brain organoids as ready-to-use products, as well as the specialized medium to support the optimal performance of the organoids. If you have any need for Brain Organoid Differentiation service, do not hesitate to contact us for this special service. Please let us know what you need and we will accommodate you. We look forward to working with you.

For research use only. Not for any other purpose.