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Over the past century, the mouse has become a key mammalian model system for genetic research due to it genetic and physiological similarities to human. And Patient-derived xenografts (PDX) are increasingly used in cancer research as a tool to inform cancer biology and drug response, which is allow for accurate and reproducible target discovery. All these models need to be molecular analyses.
Fluorescent In situ hybridization (FISH) is a great tool can be applied to differentiate between murine (host) cells and human (grafted) cells and as methods to detect mouse gene expression with morphological context in a multitude of mouse models. With years of professional experience in the FISH Probe and FISH Service field, Creative Bioarray’s streamlined process can offer timely and dependable Mouse Model and PDX Analysis (FISH) results, give you the flexibility to focus on other research priorities.
FISH can be used to confirm the targeted gene deletion or conditional knockout (KO), knockdown (KD), or knock-in mouse
Mouse models of human disease, including cardivascular disease, diabetes and obesity, colities and rare genetic diesase. FISH can be used to identify genes involved in the disease.
Humanized and patient-derived xenograft (PDX) mouse that require characterization of species-specific cell types. FISH can be used to differentiate between murine (host) cells and human (grafted) cells.
Figure 1. Gene expression analysis for any biomarkers in any tissues in mouse models
Figure 2. Human- and Mouse-Specific RNA Detection in Patient-Derived Xenografts (PDX)
Quotation and ordering
Call us today at 631-626-9181 or email us at email@example.com for a quotation or if any questions! Our customer service representatives are available 24hr a day! We thank you for choosing Creative Bioarray at your preferred Mouse Model and PDX Analysis (FISH) Services.