Organoid Drug Screening

A Robust Platform for Drug Screening

Organoid technology has emerged as a groundbreaking tool in biomedical research, revolutionizing drug screening and development. These three-dimensional (3D) cell cultures, derived from stem cells, mimic the structural and functional characteristics of human organs. By providing a closer approximation to human physiology than traditional 2D cell cultures or animal models, organoids are increasingly recognized as a reliable platform for evaluating drug efficacy and toxicity.

• Ethical Benefits: Reduces reliance on animal models for drug testing.
• Cost-Effective: Streamlines drug discovery by identifying promising compounds early.
• Personalized Medicine: Enables testing of drugs on organoids that reflect individual patient biology.

Seamlessly Acquire High-Quality Organoids for Your Research

At Creative Bioarray, we provide cutting-edge organoid drug screening solutions that combine innovation, precision, and efficiency. With our expertise, you can accelerate the drug discovery process while obtaining reliable and actionable results.

• Expert-Led Processes: Harness our expertise in organoid bioprocessing to achieve reproducible and high-quality results.
• Assay-Ready Organoids: Streamline your workflow with ready-to-use organoids, supported by our dedicated team throughout the screening process.
• On-Demand Flexibility: Access cryopreserved, quality-controlled organoids when you need them, ensuring seamless research execution.
• Customizable Quality Control: Rely on our rigorous QC processes, adaptable to meet the specific needs of your study.

Organoid Drug Screening Service Provided by Creative Bioarray

• Dose-Response Evaluation for Single Drug Treatments
  Assessing the dose-response of a single drug with organoids is a vital step in drug discovery and development. By exposing organoids to varying drug concentrations, researchers can evaluate the drug's potency, efficacy, and toxicity. This approach offers valuable insights into the compound's therapeutic window and mechanism of action, enabling more informed decisions in the development process.

Figure 1. Dose-response curves of the tested compounds.

• Exploring Drug Synergism
  Drug synergism, where two or more drugs combine to achieve effects greater than the sum of their individual actions, holds significant promise for advancing therapeutic strategies. Organoids—physiologically relevant 3D models of human tissues—provide a unique and powerful platform for studying these interactions. Leveraging organoids for drug synergy research enables researchers to:
  • Accurately predict therapeutic outcomes.
  • Optimize drug combinations for enhanced efficacy.
  • Minimize side effects through informed decision-making.

Figure 2. Typical Test Panel for Organoid Synergy Analysis

Figure 3. Synergy testing

Contact Us

At Creative Bioarray, we are dedicated to empowering your organoid drug screening projects with innovative, dependable solutions. If you have any special needs or questions regarding our services, please feel free to contact us. We look forward to cooperating with you in the future.

Explore Other Options

• 3D Spheroid & Organoid Culture Reagents
• 3D Spheroid Platform for Drug Development
• Genetic Engineering in Organoids
• Organoid Platform for Drug Development
• Organ-on-a-Chip Platform for Drug Development

• Organoid Models
• Organoid-based High-throughput Screening
• Organoid-Immune Co-Culture Models

For research use only. Not for any other purpose.