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One of the most important functions of our integument is a barrier function. The barrier function of skin can control the trans-epidermal evaporation of such essential elements as water, ions and amino acids and protect our body from invasion of a variety of allergens or external stress factors.
Skin hydration is mostly linked to the skin barrier function and is important for maintaining a healthy skin barrier. The role of a moisturizing skin care product is to act on skin surface to physically limit water loss (occlusive effect) or to act at the cellular level.
Suitable skin care products, such as skin barrier-repairing ingredients or moisturizer and etc., can help protect our skin, and can help restore skin’s barrier from skin with a compromised barrier function.
Creative Bioarray provides in vitro 3D skin tissue models and evaluation assays performed for cosmetic efficacy and claims support of reinforcing skin barrier function and hydration.
In vitro 3D skin models available
Screening assays available
Fig.1 Filaggrin expression in RHE
Fig.2 Relative humidity for different cosmetics products
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In vitro Skin Models: