Cat Tumor Cells

Cat (feline) tumor cells are essential models in veterinary oncology and comparative cancer research. Feline cancers, especially lymphomas and sarcomas, show interesting similarities with human cancers, and are thus useful for translational studies.

We maintain a selected panel of feline tumour cells for research on spontaneous and virus-associated cancers in cats, providing knowledge that bridges veterinary medicine and human oncology. These models are of great relevance to the study of retroviral pathogenesis as feline leukaemia virus (FeLV) is prevalent in cat populations.

Feline-Specific Veterinary Models Viral Oncology Translational Value

Illustration of feline anatomy or cat tumor cell culture
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Key Features & Expertise

Specialized feline tumor models for focused research

Feline Models Icon

Authentic Feline Cancer Models

  • Well-established feline cell lines including S+L-CAT2, CRFK, and PG-4
  • Representative models for key feline cancer research areas
  • Essential for veterinary oncology and comparative studies
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FeLV-Related Research Tools

  • Models for studying feline leukemia virus (FeLV) pathogenesis
  • Tools for investigating retroviral transformation in cats
  • Supports vaccine and therapeutic development
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Reliable & Characterized

  • Species-authenticated feline cell lines
  • Quality-controlled for consistent performance
  • Provided with optimized culture protocols

FAQ

What makes feline tumour cells so important for cancer research?

Feline cancers (especially lymphomas and injection-site sarcomas) are biologically very similar to human cancers. Spontaneous FeLV-associated lymphomas also occur in cats and provide a spontaneous model of retroviral carcinogenesis that is informative for veterinary and human medicine.

Can these cell lines be used for FeLV research?

Yes. S+L-CAT2 and other feline cell lines are of particular value for studies of FeLV, including virus propagation, neutralisation assays, and investigation of mechanisms of viral transformation. They are important tools for the development of diagnostics, vaccines and treatments for FeLV.

What are the primary applications of feline tumor cell lines?

Primary applications include: 1) Veterinary oncology drug research and development, 2) FeLV and feline retrovirus research, 3) Comparative oncology of feline and human cancer biology, 4) Virology and vaccine development, 5) Veterinary education.

How do I culture feline tumor cell lines?

Most feline cell lines grow well in standard media (DMEM or RPMI) containing foetal bovine serum at 37°C in the presence of 5% CO₂. Detailed protocols for each cell line are given. For example, the CRFK line is known to grow well and is commonly used for the isolation and propagation of feline viruses.

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Description: Species: cat; Transformed by: murine sarcoma virus

Cat#: CSC-6312W INQUIRY

Description: CRFK cells were isolated from the cortical portion of the kidneys of a 10-12 week old normal female ...

Cat#: CSC-C9366L INQUIRY

Description: PG-4 was derived at NIH in 1980 from G355 cells by transformation with Moloney Murine sarcoma virus ...

Cat#: CSC-C9436J INQUIRY

For research use only. Not for any other purpose.