Epigenetic Induction of Cell Growth Service

Creative Bioarray is offering epigenetic induction of cell growth service for the cell immortalization. With the Epigenetic Approach, we have established Immortalized Chicken Hepatocytes, Immortalized Monkey Hepatocytes, Immortalized Dog Hepatocytes and Immortalized Human T Cells (Cat No.: CSC-I2269Z), which their primary cells are very difficult to immortalize in traditional ways.

Epigenetic Induction of Cell Growth Service

Several methods exist for immortalizing mammalian cells in culture conditions, including SV40 T antigens, HPV-16 E6/7 gene or human telomerase reverse transcriptase (hTERT). However, some kinds of primary cells are hard to immortalized with lentiviruses or plasmids, such as hepatocytes, and immune cells (e.g., Nature Killer Cells, Dendritic Cells, CD4+ CD8+ T Cells). And many researches worry about the genomic alteration due to viral-induced expression of SV40-T Antigen or other genes. The Epigenetic Induction of Cells Growth is a great method to establish the immortalized cell lines.

Epigenetic Approach made significant breakthroughs in immune cell immortalization. To establish long-term, antigen-specific T-cell lines and clones, Creative Bioarray tried several methods for three years. In 2023, finally, we established Immortalized Human T Cells using Epigenetic Approach successfully. Immortalized Human T cells (Cat No.: CSC-I2269Z) from Creative Bioarray can be cultured continuously for 20 passages.

Now many scientists are looking for the immortalized immune cells, which are great in vitro models in drug screening. However, immune cells are difficult to immortalize. Antigen-specific T cells play a key role in cellular immune response against cancer. The ability to isolate, maintain, and characterize tumor-specific T cells is a prerequisite to studying anticancer immune response and developing novel strategies for cancer immunotherapy. However, the life span of human T cells in vitro is usually short and is limited by the onset of cellular senescence.

From this experience, Creative Bioarray has much confidence in establishing other Immortalized immune cells (e.g., Nature Killer Cells, Dendritic Cells, CD4+ CD8+ T Cells). With many years of experience and in-depth knowledge, Creative Bioarray offers Epigenetic Induction of Cell Growth Service for you. We guarantee the speed, quality and cost of our service.

Creative Bioarray's Epigenetic Induction of Cell Growth Service has the following Features:

  • No viral genes
  • No whole cell fusion unlike the production of hybridoma cell lines
  • Transfer of only non-DNA components
  • Human and animal cell lines
  • Rapid 4-6 weeks turnaround time, including addition reporting
  • Competitive pricing

Quotation and ordering

Our customer service representatives are available 24hr a day! We thank you for considering Creative Bioarray as your Epigenetic Induction of Cell Growth Service partner.

For research use only. Not for any other purpose.