Exosome Proteomics Service
Exosomes are loaded with proteins, lipids and RNAs which have been testified to vary with the pathological states of recipient organs. Several unique surface and internal proteins in exosomes may represent novel biomarkers for diseases diagnosis and prognosis. Creative Bioarray provides high quality exosomal proteomics data to profile exosomal protein composition that help you discover exosome-based biomarker candidates.
Figure 1 Workflow of mass spectrometry identification and quantitation of exosome proteins from patient serum. Schematic overview of the sample preparation and LC−MS/MS analysis of patient and control serum samples.
Figure 2 Heatmap of all protein levels in EVs normalized to their respective source cells.
We can provide:
- Exosome Isolation
- Exosome Identification
- Proteomics Analysis
- Raw MS Spectra Data
- A Detailed Report
With years' experience in the field and state-of-the-art instrumentation, Creative Bioarray provide comprehensive support to assist your exosome research. We offer the highest quality proteomics services and help you address your problems during your scientific research. Please feel free to contact us, and see how we can help you.
References
- An, M.; et al. Quantitative proteomic analysis of serum exosomes from patients with locally advanced pancreatic cancer undergoing chemoradiotherapy. J Proteome Res. 2017, 16(4): 1763-1772.
- Haraszti, RA.; et al. High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources. J Extracell Vesicles. 2016, 5: 32570.
Explore Other Options
For research use only. Not for any other purpose.
Services
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Cell Services
- Cell Line Authentication
- Cell Surface Marker Validation Service
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Cell Line Testing and Assays
- Drug-Resistant Cell Models
- Cell Viability Assays
- Cell Proliferation Assays
- Cell Migration Assays
- Soft Agar Colony Formation Assay Service
- SRB Assay
- Cell Apoptosis Assays
- Cell Cycle Assays
- Cell Angiogenesis Assays
- DNA/RNA Extraction
- Cellular Phosphorylation Assays
- Stability Testing
- Sterility Testing
- Endotoxin Detection and Removal
- Phagocytosis Assays
- Cell-Based Screening and Profiling Services
- 3D-Based Services
- Custom Cell Services
- Cell-based LNP Evaluation
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Stem Cell Research
- iPSC Generation
- iPSC Characterization
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iPSC Differentiation
- Neural Stem Cells Differentiation Service from iPSC
- Astrocyte Differentiation Service from iPSC
- Retinal Pigment Epithelium (RPE) Differentiation Service from iPSC
- Cardiomyocyte Differentiation Service from iPSC
- T Cell, NK Cell Differentiation Service from iPSC
- Hepatocyte Differentiation Service from iPSC
- Beta Cell Differentiation Service from iPSC
- Brain Organoid Differentiation Service from iPSC
- Cardiac Organoid Differentiation Service from iPSC
- Kidney Organoid Differentiation Service from iPSC
- GABAnergic Neuron Differentiation Service from iPSC
- Undifferentiated iPSC Detection
- iPSC Gene Editing
- iPSC Expanding Service
- MSC Services
- Stem Cell Assay Development and Screening
- Cell Immortalization
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Molecular Biology Solutions
- Chromosome & Genomic Analysis
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Cytogenetics & Molecular Cytogenetics Analysis
- Fluorescent In Situ Hybridization (FISH)
- In Situ Hybridization (ISH) & RNAscope
- ImmunoFISH (FISH+IHC)
- I-FISH
- Splice Variant Analysis (FISH)
- RNA FISH in Plant
- mtRNA Analysis (FISH)
- Digital ISH Image Quantification and Statistical Analysis
- Telomere Length Analysis (Q-FISH)
- Telomere Length Analysis (qPCR assay)
- Droplet Digital PCR (ddPCR)
- QuantiGene Plex Assay
- Probe Development & Quality Control
- ISH/FISH Analysis for Therapeutic R&D
- Cell Line Characterization
- Pathogen & Microbial Analysis
- Histology Services
- Exosome Research Services
- Drug Metabolism and Pharmacokinetics (DMPK)
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Safety Evaluation Services
- High-Throughput Toxicity Screening
- High-Content Cytotoxicity Screening
- In Vitro Cardiotoxicity
- In Vitro Genotoxicity
- In Vitro Hepatotoxicity
- In Vitro Neurotoxicity
- In Vitro Nephrotoxicity
- In Vitro Dermal Toxicology
- Ocular Toxicity
- In Vitro Cytotoxicity
- Endocrine Disruption Screening Assay
- In Vivo Toxicity Study