Pathogen & Microbial Analysis
Spatial characterization and organization of pathogens and microbiomes are important components of infectious disease research and microbial ecology. Viruses and microorganisms often exhibit heterogeneous localization patterns within host tissues or environmental samples, which cannot be accurately captured by bulk molecular analyses alone.
ISH and FISH-based approaches enable direct, in situ visualization of viral genomes and microbial populations at cellular resolution. By providing spatial context for pathogen presence, abundance, and interaction with their surrounding environment, these methods support mechanistic studies of infection, microbial dynamics, and host–pathogen interactions across clinical, environmental, and translational research settings.
Featured Services
Sensitive in situ detection and localization of viral nucleic acids within host cells and tissue sections.
Environmental Microorganisms Analysis (CARD-FISH)
High-sensitivity visualization of low-abundance environmental microorganisms using signal-amplified FISH methodologies.
Microorganisms Analysis (FISH)
Specific identification and spatial mapping of microbial populations in complex biological or environmental samples.
Applications
Our services support research and development in:
Viral infection and pathogenesis studies
enabling in situ localization of viral genomes in host tissues.
Clinical infectious disease research
supporting tissue-based detection of viral and microbial targets.
Environmental microbiology studies
allowing spatial analysis of low-abundance microorganisms using CARD-FISH.
Microbiome spatial profiling
visualizing microbial distribution and community organization in complex samples.
Host–pathogen interaction analysis
correlating microbial presence with host tissue architecture.
Why Choose Our Services
- Detection of low-abundance viral and microbial targets with minimal background.
- High-sensitivity in situ visualization while preserving native tissue or sample architecture.
- Compatibility with complex sample types, including FFPE tissues and environmental matrices.
- Custom probe design for diverse viral and microbial targets, including emerging pathogens.
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