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Transgene Mapping

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Analysis and confirmation of recombinant cell lines is very important. In contrast to the genes copy number, the chromosomal integration of a transgene (an exogenous gene) appears to be more considered. Due to the random nature of an integration event, several sites may be in capable of supporting the transcription of the transgene or the expression level is greatly influenced by the effect of the genetic environment at the gene locus (position effects). Fluorescence in situ hybridization (FISH) is a powerful technique that can be used to visualize transgene integration sites and provide a better understanding of transgene behavior.

With many years of experience and in-depth knowledge, Creative Bioarray can use fluorescence in situ hybridization (FISH) to confirm the integration of transgenes and determine their chromosome band location. We guarantee the speed, quality and cost of our service.

Transgene Mapping

Features of Creative Bioarray's Transgene Mapping Service:

  • cDNA (2kb~) or genomic DNA fragment on banded chromosomes
  • Species: human, mouse, rat, hamster, chicken
  • Confirm the integration of transgenes
  • Visualize chromosome band location

We can also provide Transgene Mapping with M-FISH, which is a technique to determine chromosomes.


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CONTACT US USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
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Europe
Tel: 44-207-097-1828
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