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Atopic dermatitis (AD) is a chronic, pruritic inflammatory skin disease of unknown origin that usually starts in early infancy, but also affects a substantial number of adults. Left untreated, the barrier function of the skin is compromised, increasing susceptibility to dehydration and infection. It is so common and also known as Eczema, Dermatitis, Atopic eczema. Since the 2000s, the discovery of a preventive treatment for this severe dermatosis has been a special line of research in the pharmaceutical, dermatological and cosmetics industry.
Pathogenesis of acute atopic dermatitis
Creative Bioarray team dedicates in developing and validating predictive in vitro pharmacological testing for screening or evaluating potential modulators of atopic dermatitis (APIs, biosimilars, formulations, medical devices) before clinical trials.
Creative Bioarray provides in vitro 3D skin tissue models and evaluation assays performed for pharmaceutical, dermatological and cosmetics industries to help screening modulators of atopic dermatitis.
In vitro 3D skin models available
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In vitro Skin Models: