Astrocytes have a central role in brain development and function, and so have gained increasing attention over the past two decades. Consequently, our knowledge about their origin, differentiation and function has increased significantly, with new research showing that astrocytes cultured alone or co-cultured with neurons have the potential to improve our understanding of various central nervous system diseases, such as amyotrophic lateral sclerosis, Alzheimer’s disease, or Alexander disease. The generation of astrocytes derived from pluripotent stem cells (PSCs) opens up a new area for studying neurologic diseases in vitro, these models could be exploited to identify and validate potential drugs by detecting adverse effects in the early stages of drug development.
Figure 1. Schematic of iPSC-derived neuronal and glia cells.
Our Astrocyte Differentiation Service includes:
- Robust, mature astrocytes with morphology of primary astrocytes
- Cells express key astrocyte specific markers: GFAP and S100beta; other markers available upon request
- Differentiate from your healthy, disease or engineered iPSCs
- "Master" iPSCs available for deriving control astrocyte lines
- Optional! Cell Line validation and drug screening services available
Requirements: 5 vials (2.5 million cells per vial) of hiPS or hES cells
- Cryopreserved iPSC-derived astrocytes: >90% GFAP+; S100beta+
- Project Report
Turnaround time: 8-10 weeks
Figure 2. Comparison between Human iPSC-Derived Astrocytes and Primary Astrocytes.
Creative Bioarray is an experienced and outstanding provider of Astrocyte Differentiation service and differentiation kit. We are dedicated to providing quality data and comprehensive service for your scientific research, and we are pleased to use our extensive experience and advanced platform to offer the best service to satisfy each demand from our customers.
If you have any special need in Astrocyte Differentiation service, do not hesitate to contact us for this special service. Please let us know what you need and we will accommodate you. We look forward to working with you in the future.
For research use only. Not for any other purpose.