Pulmonary Cells
The respiratory system comprises highly specialized epithelial, stromal, vascular, and smooth muscle cell populations that work together to maintain gas exchange, airway function, tissue repair, and immune defense. Alterations in these cellular networks contribute to a broad range of pulmonary disorders, including asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), pulmonary hypertension, and lung cancer.
Our pulmonary cell portfolio includes primary airway epithelial cells, alveolar epithelial cells, fibroblasts, endothelial cells, smooth muscle cells, disease-specific respiratory models, and tumor-associated cell populations. These physiologically relevant resources support research in respiratory biology, airway remodeling, pulmonary vascular disease, inflammation, oncology, regenerative medicine, and drug discovery.
20 +
Disease-Relevant
Cell Models
100 %
Mycoplasma-Free
Tested
6 +
Respiratory Research
Applications
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Our Pulmonary Cell Portfolio Highlights
Comprehensive Pulmonary Cell Resources
Our collection encompasses key cellular components of the airway, alveolar, stromal, and pulmonary vascular microenvironments.
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Airway and Alveolar Cell Models
- Bronchial, airway, and alveolar epithelial cells
- Type I and Type II alveolar epithelial cells
- Models for airway barrier and respiratory function studies
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Pulmonary Vascular Cell Resources
- Pulmonary artery, pulmonary vein, and microvascular endothelial cells
- Pulmonary smooth muscle cells and vascular fibroblasts
- Models for vascular remodeling and angiogenesis research
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Disease and Reporter Cell Models
- Asthma, COPD, cystic fibrosis, hypertension, and diabetic pulmonary models
- Tumor-associated endothelial and fibroblast models
- GFP- and RFP-expressing pulmonary cell populations
Applications in Respiratory Research
These models support investigations spanning pulmonary physiology, disease mechanisms, and translational therapeutic development.
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Airway Disease Research
Support studies of asthma, COPD, cystic fibrosis, airway inflammation, epithelial barrier function, and airway remodeling.
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Pulmonary Vascular Biology
Investigate endothelial dysfunction, vascular remodeling, angiogenesis, and mechanisms associated with pulmonary hypertension.
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Lung Cancer Microenvironment Studies
Explore interactions among tumor epithelial cells, fibroblasts, endothelial cells, and surrounding stromal components.
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Drug Discovery and Translational Research
Enable target validation, efficacy evaluation, toxicity assessment, and development of novel respiratory therapeutics.
What pulmonary cell types are commonly used for airway disease research?
Airway epithelial cells, bronchial smooth muscle cells, lung fibroblasts, and small airway epithelial cells are frequently used to investigate asthma, COPD, cystic fibrosis, airway remodeling, inflammatory signaling, and epithelial barrier function.
What is the difference between Type I and Type II alveolar epithelial cells?
Type I alveolar epithelial cells primarily facilitate gas exchange across the alveolar surface, whereas Type II alveolar epithelial cells produce pulmonary surfactant and contribute to alveolar repair and regeneration following lung injury.
How can pulmonary vascular cells support pulmonary hypertension research?
Pulmonary artery endothelial cells, smooth muscle cells, fibroblasts, and microvascular endothelial cells are widely used to study vascular remodeling, endothelial dysfunction, inflammatory responses, and mechanisms associated with pulmonary hypertension.
Do you provide disease-specific respiratory cell models?
Yes. Our portfolio includes pulmonary cell models associated with asthma, COPD, cystic fibrosis, pulmonary hypertension, diabetes-related vascular complications, and lung cancer microenvironment studies.
What cell types are suitable for lung tumor microenvironment studies?
Researchers commonly combine lung carcinoma epithelial cells, cancer-associated fibroblasts, tumor-associated endothelial cells, and stromal cell populations to investigate tumor progression, angiogenesis, therapeutic resistance, and cell-cell communication.
What are GFP- and RFP-expressing pulmonary cells used for?
Fluorescently labeled pulmonary cells are valuable for live-cell imaging, migration studies, angiogenesis assays, cell tracking, co-culture experiments, and visualization of cell-cell interactions in both 2D and 3D models.