Smooth Muscle Cells
Coronary Artery Smooth Muscle Cells
Coronary artery disease is the leading cause of death worldwide, but there is currently no effective method to regenerate new coronary arteries in a sick or injured heart. This may be due to our limited understanding of coronary artery progenitor cells and the signaling pathways that activate their differentiation. Coronary arteries are vessels that supply blood to the ventricular myocardium and consist of an endothelial cell lining wrapped by a smooth muscle covering. Coronary artery smooth muscle cells are particularly important due to their role in the pathogenesis of coronary artery disease. They provide an excellent model system for studying various aspects of cardiovascular function and disease, especially those related to the hyperplasia and hypertrophy of intimal smooth muscle cells leading to vascular occlusion in atherosclerosis and stent restenosis.
Airway Smooth Muscle Cells
Airway smooth muscle cells may play an important role in the interaction with inflammatory cells and other structural cells. Such a recognition makes it necessary to consider airway smooth muscle as a target of therapeutic drugs to inhibit the contraction, proliferation and secretion of asthma. Cultured airway smooth muscle cells have provided a convenient model system for studying the regulation of a wide range of airway responses at the cellular level.
Creative Bioarray provides high-quality airway smooth muscle cells, which are isolated from the trachea or sometimes from the major bronchia and cryopreserved at P1. Diseased airway smooth muscle cells are also available from donors diagnosed with asthma, COPD and cystic fibrosis.
Bladder Smooth Muscle Cells
The urinary bladder is a hollow organ composed of smooth muscle cells. The contraction and relaxation of urinary bladder smooth muscle cells allow the bladder to store and void urine respectively. Phenotypic modulation of bladder smooth muscle cells and the expression of inducible nitric oxide synthase are associated with a variety of pathological conditions. Therefore, understanding the changes in smooth muscle cells during the genesis and maintenance of the disease is essential for the development of therapeutic approaches.
Primary bladder smooth muscle cells are excellent models for studying interstitial cystitis, bladder infection, urinary incontinence, bladder cancer, and bladder reconstruction. Special donor profiles and characteristics, such as age, sex, race and source are available on request.
Description: Aged Mouse Aortic Smooth Muscle Cells are isolated from aorta of pathogen-free laboratory mice of ...
Description: Aged Mouse Artery Smooth Muscle Cells are isolated from artery of pathogen-free laboratory mice of ...
Description: Aged Mouse Bladder Smooth Muscle Cells are isolated from bladder of pathogen-free laboratory mice ...
Description: Aged Mouse Brain Vascular Smooth Muscle Cells are isolated from brain vascular of pathogen-free ...
Description: Aged Mouse Colonic Smooth Muscle Cells are isolated from colon of pathogen-free laboratory mice of ...
Description: Aged Mouse Coronary Artery Smooth Muscle Cells are isolated from coronary artery of pathogen-free ...
Description: Aged Mouse Esophageal Smooth Muscle Cells are isolated from esophagus of pathogen-free laboratory ...
Description: Aged Mouse Ovarian Smooth Muscle Cells are isolated from ovarian of pathogen-free laboratory mice ...
Description: Aged Mouse Prostate Smooth Muscle Cells are isolated from prostate of pathogen-free laboratory mice ...
Description: Aged Mouse Pulmonary Artery Smooth Muscle Cells are isolated from pulmonary artery of pathogen-free ...
Description: Aged Mouse Small Intestinal Smooth Muscle Cells are isolated from small Intestine of pathogen-free ...
Description: Aged Mouse Stomach Intestinal Smooth Muscle Cells are isolated from stomach of pathogen-free ...
Description: Aged Mouse Tracheal Intestinal Smooth Muscle Cells are isolated from trachea of pathogen-free ...
Description: Aged Mouse Vein Intestinal Smooth Muscle Cells are isolated from vein of pathogen-free laboratory ...
Description: Cynomolgus Monkey Uterine Smooth Muscle Cells from Creative Bioarray are isolated from uterine ...
Description: Cynomolgus Monkey Stomach Smooth Muscle Cells from Cretive Bioarray are isolated from the stomach ...
Description: Cynomolgus Monkey Small Intestinal Smooth Muscle Cells from Creative Bioarray are isolated from the ...
Description: Cynomolgus Monkey Pulmonary Vein Smooth Muscle Cells from Creative Bioarray are isolated from the ...