Neurological Disease Models
Preclinical in vivo platforms for neurodegeneration, neuroinflammation, CNS injury, and neuropsychiatric disorder research. Comprehensive and reproducible animal models supporting drug discovery, mechanism studies, and translational neuroscience.
Neurological Disease Model Categories
Organized across neurodegeneration, psychiatric disorders, CNS injury, vascular diseases, and epilepsy research.
Neurodegenerative Disease Models
Epilepsy ＆ Seizure Models
Neuropsychiatric & Neurodevelopmental Disorder Models
Cerebrovascular Disease Models
Comprehensive Neurological Assessment Endpoints
Multidimensional in vivo and in vitro analysis for functional, structural, and molecular evaluation.
Behavioral & Functional Assessments
- Morris water maze
- Rotarod
- Open field test
- Forced swim test
- Grip strength
- Social interaction test
Histopathology & Imaging Analysis
- H&E / Nissl staining
- IHC / IF
- Amyloid plaque analysis
- Neuroinflammation markers
- IVIS imaging
Molecular & Cellular Analysis
- ELISA
- Western blot
- qPCR
- RNA sequencing
Biofluid Biomarkers
- CSF biomarkers
- Cytokine profiling
- Neurofilament light chain (NfL)
- Serum/plasma biomarker analysis
Why Choose Our Neurological Disease Model Platform
- Extensive disease coverage across CNS disorders
- Validated and highly reproducible animal models
- Multidimensional behavioral, molecular, and imaging endpoints
- Experienced neuroscience research team
- Integrated pharmacology, pathology, and biomarker services
FAQ
What neurological disease models do you offer?
We focus on important CNS disease areas including neurodegenerative illnesses (Alzheimer's, Parkinson's, ALS, Huntington's), neuropsychiatric & neurodevelopmental diseases (schizophrenia, depression, Tourette syndrome), CNS injuries (TBI, spinal cord injury, HIE), cerebrovascular diseases (stroke, ICH) and seizure models. Each model is designed to replicate the major pathology and behavioral features of human disease.
Which species are available for neurological disease models?
We primarily offer rodent-based models, including mice and rats, which are widely used in neuroscience research due to their well-characterized genetics and behavioral phenotypes. In addition, transgenic and knockout mouse models are available for specific disease mechanisms.
Can you provide transgenic or genetically engineered models?
Yes. We offer a wide selection of transgenic, knockout and knock-in mice models related to neurological illnesses. These include models of amyloid processing, tau pathology, dopaminergic neurodegeneration, neuroinflammation, and synaptic dysfunction.
Do you support behavioral and functional assessments?
Yes. Behavioral and functional testing is a key part of our neurological disease model platform. We provide full evaluation panels including cognitive, motor coordination, emotional behavior, anxiety-related behavior and social interaction.
Common tests include Morris water maze, rotarod, open field test, forced swim test, grip strength analysis and social interaction assays.
How long does it take to establish a neurological disease model?
Model establishment timelines vary depending on disease type, induction method, and study complexity. Acute models such as seizure or stroke can often be established within days to 1–2 weeks, while chronic neurodegenerative models (e.g., Alzheimer's or Parkinson's disease) may require several weeks to months to develop stable phenotypes.
We also provide accelerated study designs and pre-validated model cohorts to support time-sensitive projects.