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MIA PaCa-2
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Cat.No.
CSC-C9492L
Description
The MIA PaCa-2 cell line was established from tumor tissue of the pancreas obtained from a 65-year-old Caucasian male in 1975 by A. Yunis, et al. These cells are described to express human colony stimulating factor, subclass I (CSF-I) and plasminogen activator. The established cell line reportedly has a doubling time of about 40 hours and a colony-forming efficiency in soft agar of approximately 19%. Sensitive to L-Asparaginase.
Species
Homo sapiens (human)
Tissue of Origin
Pancreas
Culture Properties
monolayer with floating cells
Morphology
Epithelial-like
STR DNA Profile
Amelogenin: X
CSF1PO: 10
D13S317: 12,13
D16S539: 10,13
D5S818: 12,13
D7S820: 12,13
THO1: 9,10
TPOX: 9
vWA: 15
CSF1PO: 10
D13S317: 12,13
D16S539: 10,13
D5S818: 12,13
D7S820: 12,13
THO1: 9,10
TPOX: 9
vWA: 15
Karyotype
This is a hypotriploid human cell line. The modal chromosome number is 61. Sixteen to 20 marker chromosomes are commonly found in a cell. A few normal chromosomes are absent.
Applications
The MIA PaCa-2 cell line can be used as tumourigenicity and enzymatic studies.
Disease
Carcinoma
Quality Control
Tests for mycoplasma, bacteria and fungi were negative
Storage and Shipping
Frozen with 52.5% RPMI-1640, 40% FBS, 7.5% DMSO at about 4-5 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
Can tumor stem cells give rise to different types of cancer cells within a tumor?
A:
Yes, tumor stem cells can differentiate into different cell types found within a tumor. This differentiation process can lead to the formation of heterogeneous tumor cell populations, each exhibiting different characteristics and behavior.
Average Rating: 5.0 | 1 Scientist has reviewed this product
Promote delivery
The tumor cell product was delivered very quickly after I ordered it online. I was able to start my research immediately.
21 Nov 2022
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