Osteoporosis Model
Creative Bioarray specializes in providing various osteoporosis models tailored for preclinical research. Our team of experts employs cutting-edge techniques to develop and validate these models, ensuring their relevance and reliability for your research needs. Whether you are studying the effects of investigating the mechanisms of glucocorticoid-induced osteoporosis or evaluating novel therapeutic interventions, we have the perfect model to support your scientific goals. Choose us for your osteoporosis research and experience the difference our expertise and dedication can make in advancing your preclinical research.
Osteoporosis, a common bone disorder, is characterized by an imbalance between bone resorption and bone formation, leading to a net loss of bone mineral density (BMD). This condition increases the risk of fractures, particularly in the hip, spine, and forearm. Multiple risk factors have been identified, including sex hormones, aging, lifestyle factors, and the use of certain medications such as glucocorticoids and some anticonvulsants. Given the prevalence and impact of osteoporosis, numerous drugs and therapeutic approaches have been investigated for its treatment.
Fig. 1 Pharmacological action sites for osteoporosis
To advance our understanding and develop effective treatments for osteoporosis, preclinical research utilizing osteoporosis animal models is crucial. These models mimic human disease and allow for the evaluation of potential therapies in a controlled setting.
Our Animal Models of Osteoporosis
Osteoporosis is a common bone disease characterized by low bone mass and structural deterioration of bone tissue, leading to an increased risk of fractures. This condition affects millions of people worldwide, particularly postmenopausal women and older adults. To accelerate the development of new therapies and to better understand the mechanisms underlying this disease, Creative Bioarray offers a range of osteoporosis models tailored to meet the specific needs of researchers. These models include:
- Ovariectomy (OVX)-Induced Osteoporosis Model
- Orchiectomy (ORX)-Induced Osteoporosis Model
- Glucocorticoid-Induced Osteoporosis (GIO) Model
Quotation and Ordering
At Creative Bioarray, you will find the most comprehensive preclinical services at the most competitive prices. We are willing to share our extensive experience in drug efficacy studies to help you achieve your research goals. Whether you're seeking guidance on study design, assistance with disease model development, or need help interpreting your data, we are here to support you every step of the way. If you are interested in our services, please feel free to contact us at any time or submit an inquiry to us directly.
Reference
- Kim, B., et al. Osteoporosis therapies and their mechanisms of action. Experimental and therapeutic medicine, 2021, 22(6): 1-14.
