Electron Microscopy Services
Unlock nanoscale structural details with our advanced electron microscopy services. Our TEM and SEM-based particle size analysis provides precise characterization of nanomaterials, while negative staining TEM offers rapid macromolecular visualization. For near-native state imaging, cryo-TEM and single-particle cryo-EM enable high-resolution 3D reconstructions of biomolecules. Immuno-TEM combines ultrastructural imaging with targeted antigen detection, and high-resolution SEM reveals intricate surface morphology. Whether for structural biology, materials science, or pathology, our cutting-edge microscopy solutions deliver unparalleled clarity and precision.
Our Services
Transmission Electron Microscopy (TEM)
Enables nanometer-scale visualization of internal ultrastructure for detailed analysis of cells, viruses, and nanomaterials.
Scanning Electron Microscopy (SEM)
Surface topography and morphology imaging with exceptional depth of field for detailed material and tissue characterization.
Particle Size Analysis (TEM, SEM）
Provides images of intracellular ultrastructure, viruses, organelles, and nanoparticle morphology for cell biology, virology, and nanomaterial characterization.
Offers a fast method for screening particle integrity, shape, and size uniformity for proteins, EVs, viruses, and lipid-based delivery systems.
Cryogenic Transmission Electron Microscopy (cryoTEM)
Captures specimens in a vitrified, near-native state—essential for soft nanomaterials, EVs, viral particles, and formulation stability assessment.
Produces high-resolution 3D reconstructions of protein complexes without crystallization. Widely applied in mechanism studies and structure-based drug discovery.
Immuno Transmission Electron Microscopy (immunoTEM)
Nanogold labeling enables localization of molecules within cellular ultrastructure, for studies of pathways, receptors, or target validation.
Delivers atomic-level structural insights from nanocrystals using minimal sample amounts, providing an efficient alternative when conventional crystallography is not feasible.
High-Resolution Imaging Capabilities
| Resolution | Key Strengths | Typical Applications | |
|---|---|---|---|
| Negative Staining TEM | 10–20 Å (effective) | Rapid sample screening | Virus morphology, protein aggregates |
| Cryo-TEM | Sub-nanometer (~5–10 Å) | Near-native hydration preservation | Membrane proteins, liposomes |
| Single-Particle Cryo-EM | ~2–4 Å (near-atomic) | High-resolution 3D reconstruction | Macromolecular complexes, drug binding |
| Immuno-TEM | ~5–10 nm localization accuracy | Target-specific ultrastructural localization | Subcellular organelle mapping |
| SEM (Standard) | 1–5 nm | Surface topography | Cell membranes, nanomaterials |
| TEM Particle Size Analysis | ~1 nm–several μm | Quantitative size/distribution statistics | Nanoparticle drug carriers |
Explore Other Options
