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BLUE-1
- Specification
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Cat.No.
CSC-C0597
Description
Established from the bone marrow of a 29-year-old Caucasian man with Burkitt lymphoma in second relapse following combined chemotherapy and radiotherapy in 2004; cells are described to carry t(6;20)(q15;q11.2) leading to BACH2-BCL2L1 fusion gene
Species
Human
Source
bone marrow
Culture Properties
suspension
Morphology
round cells growing singly or in clumps in suspension
Karyotype
Human hyperdiploid karyotype; 53(49-53)<2n>XY, +6, +13, +16, +20, +20, +20, +21, t(6;20)(q15;q11.2), der(6)t(6;20)(q15;q11.2), t(8;14)(q24;q32), der(20)del(20)(p12.2p13.2)t(6;20)(q15;q11.2)t(6;11)(q16;p13)x2; carries t(8;14) effecting IGH@-MYC juxtapositi
Quality Control
Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD3 -, CD13 -, CD19 +, CD20 -, CD34 -, CD37 +, CD38 +, cyCD79a +, CD80 -, CD138 -, HLA-DR +, sm/cyIgG +, sm/cyIgM -, cykappa -, cylambda +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HT
Immunology: CD3 -, CD13 -, CD19 +, CD20 -, CD34 -, CD37 +, CD38 +, cyCD79a +, CD80 -, CD138 -, HLA-DR +, sm/cyIgG +, sm/cyIgM -, cykappa -, cylambda +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HT
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 10-15 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
Can tumors be polyclonal?
A:
Polyclonal tumors might become established at a higher frequency than monoclonal tumors because interactions between initiated clones alter the microenvironment. Molecule-mediating interactions within a polyclonal tumor might also be critical for tumor progression.
Average Rating: 4.0 | 1 Scientist has reviewed this product
High-quality
The tumor cells arrived in perfect condition and have exceeded our expectations in terms of quality.
10 Apr 2023
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