TMPRSS2-ERG Deletion, Triple-Color, Break Probe

FONC-113

The TMPRSS2-ERG probe is designed as deletion probe, where loss of the proximal TMPRSS2 region is observed as loss of a green signal leaving a red/blue signal at 21q22. Split of the probe in case of a translocation at 21q22 results in a break of the fusion signal, observed as a single red and green/blue signal pattern at the derivative chromosomes, when only TMPRSS2 is involved. And observed as a single blue and red/green signal pattern at the derivative chromosomes, when only ERG is involved. Only red and green/blue signals which are more than one signal diameter apart from each other are counted as a break. Single color fusion (RGB) signals will identify the normal chromosomes 21.

10 Tests

Red/Green/Blue

Human

21q22

For Research Use Only. Not for use in diagnostic procedures.

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