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MET Probe
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Cat.No.
FONC-080
Description
The MET Probe Kit is based on the ability of MET locus-specific identifier (LSI) probe to identify copy number changes of 7q31.2 chromosomal locus, using a FISH test.
MET is a Receptor Tyrosine Kinase. It binds to the ligand, Hepatocyte Growth Factor (HGF). The MET pathway regulates many cellular responses including cell proliferation, survival, motility, invasion and morphogenesis. This pathway is one of the most frequently dysregulated pathways in human cancer for both solid tumors and hematological malignancies including gastric, head and neck, liver, ovarian, non-small cell lung (NSCL) and thyroid cancers, as well as in metastases of some of these cancers.
MET has been shown to be frequently overexpressed or amplified in many cancers, including brain, colorectal, gastric, lung, head and neck and stomach cancers.
MET is a Receptor Tyrosine Kinase. It binds to the ligand, Hepatocyte Growth Factor (HGF). The MET pathway regulates many cellular responses including cell proliferation, survival, motility, invasion and morphogenesis. This pathway is one of the most frequently dysregulated pathways in human cancer for both solid tumors and hematological malignancies including gastric, head and neck, liver, ovarian, non-small cell lung (NSCL) and thyroid cancers, as well as in metastases of some of these cancers.
MET has been shown to be frequently overexpressed or amplified in many cancers, including brain, colorectal, gastric, lung, head and neck and stomach cancers.
Size
20 Tests
Label
Red/Green
Locus
7q31.2
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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