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D20S108 Probe

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Cat.No.
FHPC-041
Description
The D20S108 fluorescence in situ hybridization (FISH) probe is intended to detect deletions of D20S108 probe target locus on 20q12. Cytogenetic analysis of del(20q) revealed that the deletion is variable in size, with a commonly deleted region (CDR) spanning 20q11.2 to q12. Within the commonly deleted segment lies the SRC oncogene and possibly other tumor suppressor genes. The CDR is defined as a 2.7 Mb segment in MPD and a 2.6 Mb segment in AML/MDS, with an overlapping region of 1.7 Mb.
Among MDS, MPD and MDS/MPD groups, Douet-Guilbert et al identified one commonly deleted region in all 38 investigated samples using FISH.
Size
20 Tests
Label
Red/Green
Locus
20q12
Specificity
Human
Usage
warningFor Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.
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CONTACT US USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
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Europe
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