Featured Products
- Adipose Tissue-Derived Stem Cells
- Human Neurons
- Mouse Probe
- Whole Chromosome Painting Probes
- Hepatic Cells
- Renal Cells
- In Vitro ADME Kits
- Tissue Microarray
- Tissue Blocks
- Tissue Sections
- FFPE Cell Pellet
- Probe
- Centromere Probes
- Telomere Probes
- Satellite Enumeration Probes
- Subtelomere Specific Probes
- Bacterial Probes
- ISH/FISH Probes
- Exosome Isolation Kit
- Human Adult Stem Cells
- Mouse Stem Cells
- iPSCs
- Mouse Embryonic Stem Cells
- iPSC Differentiation Kits
- Mesenchymal Stem Cells
- Immortalized Human Cells
- Immortalized Murine Cells
- Cell Immortalization Kit
- Adipose Cells
- Cardiac Cells
- Dermal Cells
- Epidermal Cells
- Peripheral Blood Mononuclear Cells
- Umbilical Cord Cells
- Monkey Primary Cells
- Mouse Primary Cells
- Breast Tumor Cells
- Colorectal Tumor Cells
- Esophageal Tumor Cells
- Lung Tumor Cells
- Leukemia/Lymphoma/Myeloma Cells
- Ovarian Tumor Cells
- Pancreatic Tumor Cells
- Mouse Tumor Cells
Hot Products
D13S319 Deletion Probe
- Specification
- Q & A
- Customer Review
Cat.No.
FHPC-038
Description
Chromosomal abnormalities on chromosome 13q occur in 16 - 40% of multiple myeloma cases and are associated with poor prognosis. Deletions affecting the 13q14 band are also the most frequent genetic abnormalities of B-cell Chronic Lymphocytic Leukaemia. Two non-coding RNA genes, DLEU1 and DLEU2 and the genetic marker D13S319 span the pathogenic critical region 13q14.3. DLEU1 is considered to be the most likely CLL-associated candidate tumour suppressor gene within the 13q14 region. Subsequently the locus D13S319, located between the RB1 gene and D13S25 and within the DLEU1 locus, was found to be deleted in 45% of CLL cases. The D13S319 deletion probe covers the marker and the centromeric end of the DLEU1 locus.
Size
5 Tests, 10 Tests
Label
Red/Green
Specificity
Human
Locus
13q14.3
Usage

Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
If your paper has been published, please click here
to submit the PubMed ID of your paper to get a coupon.
Ask a Question
Write your own review