Description
The CCND1 Dual Color Break Apart Rearrangement FISH probe is intended to detect chromosomal rearrangements involving the Cyclin D1 (CCND1) gene region at chromosome 11q13.
Mantle cell lymphoma (MCL) is an aggressive B-cell lymphoma and is commonly characterized by over-expression of CCND1 resulting from the t(11;14)(q13;q32) translocation. Over-expression of CCND1, which can result from chromosomal anomalies such as translocations or gain of the involved area, have been found to occur in multiple myeloma (MM) and MCL. The CCND1 Dual Color Break Apart Rearrangement Probe has been used to help identify rearrangement in the CCND1 breakpoint region in MCL.
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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