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BCR/ABL Translocation, Dual Fusion Probe
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Cat.No.
FHPC-020
Description
The presence of the Philadelphia chromosome, produced as a result of the Philadelphia translocation t(9;22)(q34;q11), has important detective implications in a number of Haematological disorders. The abnormality is characteristic of CML (found in around 90% of cases) but represents a significant abnormality in 30% of adult and 2 to 10% of childhood ALL cases. This rearrangement is also seen in rare cases of AML. The stereotypic translocation fuses the ABL1 proto-oncogene to the BCR gene, giving rise to the BCR/ABL1 fusion gene, which encodes for tyrosine kinase.
Size
5 Tests, 10 Tests
Label
Red/Green
Locus
9q34/22q11
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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