USA USA: 1-631-626-9181 Europe Europe: 44-207-097-1828  

Search

Tissue samples, tissue arrays, cells, microorganisms, probes and services for your research.

Web Search    Google
Featured Products
Ordering Information

Payment methods we support:
✭ Invoice / Purchase Order
✭ Credit card


BCL2 Breakapart Probe

  • Specification
  • Recommended Products
Cat.No.
FHPC-013
Description
The BCL2 (18q21) Break probe is optimized to detect translocations involving the BCL2 gene region at 18q21 in a dual-color, split assay.
The B-cell CLL/Lymphoma 2 (BCL2) gene located at 18q21.33 encodes for a large protein family that regulate and contribute to programmed cell death or apoptosis by controlling the mitochondrial membrane permeability. Translocations of the BCL2 gene result in constant expression of the BCL2 protein. The t(14;18) is observed in 70-95% of Follicular Lymphoma (FL) cases and 20-30% of Diffuse Large B-cell Lymphoma (DLBCL). Presence of the t(14;18) translocation in DLBCL is a predictor of reduced overall and disorder free survival.
Size
5 Tests, 10 Tests
Label
Red/Green
Locus
18q21.33
Specificity
Human
Usage
warningFor Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.
Customer Support & Price Inquiry
Please input "bioarray" as verification code.
CONTACT US USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: 

Europe
Tel: 44-207-097-1828
Email: