This fluorescence in situ hybridization (FISH) probe is intended to detect the copy number of the LSI 13q34 probe target located at chromosome 13q34.
Genetic aberrations of chromosome 13, especially 13q- and monosomy, are common in hematopoietic disorders. Deletions of 13q14 have been detected in 30-50% of multiple myeloma samples. The differentiation of an interstitial deletion from loss of the entire q arm is made difficult for lack of a more telomeric marker. The 13q34 probe is located near the telomere region of the q arm. This Probe has been used to detect copy number abnormalities of the 13q34 probe target in multiple myeloma samples.
For Research Use Only. Not for use in diagnostic procedures.
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