Chromosomal abnormalities on chromosome 13q occur in 16 - 40% of multiple myeloma cases. Deletions affecting the 13q14 band are also the most frequent genetic abnormalities of B-cell Chronic Lymphocytic Leukaemia (B-CLL).
This probe contains unique DNA sequences specific to the RB1 gene within the 13q14 region of chromosome 13. The presence or absence of the RB1 gene region may be detected using the LSI 13 (RB1) 13q14 Probe. This probe may be used to detect deletion (not mutation) of the RB1 gene locus.
For Research Use Only. Not for use in diagnostic procedures.
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