GMF-gamma is a hematopoietic-specific protein that mediates pluripotentiality and lineage commitment of human hematopoietic stem cells. Glia maturation factor gamma is a cytokine- responsive protein in EPO-induced and G-CSF-induced hematopoietic lineage development. It also acts as a Nerve Growth Factor in nervous system development, angiogenesis and immune function. GMF-gamma possesses hematopoietic tissue-specific gene expression, a promoter concentrated with high-score hematopoiesis-specific transcription factors, and molecular co- evolution with a rudimentary blood/immune system. Recombinant human GMF-gamma produced in E. coli is a signle, non-glycosylated, polypeptide chain containing 142 amino acids and having a total molecular mass of 16.8 kDa.
Human GMFG expressed in E.coli
CAT# CSC-CTK0157-20 (20 μg); CAT# CSC-CTK0157-100 (100 μg)
Greater than 90% as determined by SDS-PAGE analysis.
Sterile-filtered, colorless, clear solution containing 20 mM Tris-HCl (pH 8), 1 mM DTT, 1 mM EDTA and 10% glycerol.
Please centrifuge product briefly before opening vial. The dissolved protein can be diluted into other aqueous buffers and stored at -20°C for future use.
Storage & Stability
Store at 4°C if entire vial will be used within 4 weeks. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
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