High-Throughput Toxicity Screening

At Creative Bioarray, drug candidates can be screened on a large scale for their cytotoxicity through our cell-based high-throughput screening platforms. Our screening assay can be rapidly carried out in both 2D cell monolayers and 3D spheroids to provide reliable toxicity data according to the needs of you study. With our highly experienced scientific team and state of the art equipment, we are able to develop new assays, make adjustment to our existing services, and perform post-assay experiments to fully meet the needs of our clients.

Drug toxicity is the main cause for drug attrition and drug withdrawal during the drug development process. Drug toxicity screening at an early stage can help avoid fruitless time and money input on unpromising candidates. Compared to costly in vivo toxicity tests, cell-based toxicity assays have many advantages: short turn-around time, high reproducibility, low covariance, cost and time efficiency, easy to carry out, and suitable for mechanistic studies.

High-throughput screening is a widely used method in drug discovery that can rapidly identify effective compounds from a large number of hits or drug candidates. This method can be applied to the screening or profiling of the effectivity, cytotoxicity, ADME property, and other properties of candidate compounds. High-throughput toxicity screening can quickly narrow down a long list of candidate compounds by assessing their in vitro toxicity on a large scale, and boost the process of drug discovery.

Staffed with a group of well-experienced scientists in drug discovery and high-throughput screening, Creative Bioarray is able to provide:

• Toxicity screening using well-established cell lines or primary cell lines
• Toxicity screening using 3D cell cultures
• Post-assay experiments
• Detailed report of cytotoxicity results
• Raw data and images obtained in the assay
• Customized services

Creative Bioarray aims at providing our clients with services and scientific data of the highest quality. Please feel free to contact us and let us know your needs or any questions you have regarding this service. Our experts will answer your questions as soon as possible and work closely with you to come up with a suitable solution especially for you. We look forward to working with you in the future.