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TOM-1
- Specification
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Cat.No.
CSC-C0583
Description
Established in 1983 from the bone marrow of a 54-year-old woman with refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL); described to carry the ALL-variant (m-bcr) of the BCR-ABL1 fusion gene (e1-a2)
Species
Human
Source
B cell precursor leukemia
Culture Properties
suspension
Morphology
small round cells growing in suspension singly or in clumps, some cells are loosely adherent
Karyotype
Human hyperdiploid karyotype with 7% polyploidy - 47(47-48)<2n>X, -X, +8, +16, del(7)(p14), der(9)del(9)(q13q34)t(9;22)(q34;q11), der(22)t(9;22)(q34;q11) - carries t(9;22) effecting BCR-ABL1 rearrangement - resembles published karyotype
Quality Control
Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD2 -, CD3 -, CD4 -, CD7 -, CD10 +, CD13 +, CD19 +, CD20 +, CD34 +, CD37 +, CD38 +, cyCD79a +, CD80 -, CD138 -, HLA-DR +, sm/cyIgG -, sm/cyIgM -, sm/cykappa -, sm/cylambda -
Viruses:
Immunology: CD2 -, CD3 -, CD4 -, CD7 -, CD10 +, CD13 +, CD19 +, CD20 +, CD34 +, CD37 +, CD38 +, cyCD79a +, CD80 -, CD138 -, HLA-DR +, sm/cyIgG -, sm/cyIgM -, sm/cykappa -, sm/cylambda -
Viruses:
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 6 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
What are the three types of FISH probes?
A:
There are broadly three types of probes, each with a different range of applications, whole-chromosome painting probes, repetitive sequence probes, and locus-specific probes.
Average Rating: 5.0 | 1 Scientist has reviewed this product
High-quality
The quality of the tumor cells is exceptional and has allowed us to conduct accurate experiments.
19 Oct 2022
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