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VCAP

  • Specification
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Cat.No.
CSC-C8204L
Description
This cell line was established from prostate cancer tissue harvested from a metastatic lesion to a lumbar vertebral body of a patient with hormone refractory prostate cancer. The cells are reported to express large quantities of prostate specific antigen (PSA). This cell line also expresses prostatic acid phosphatase (PAP), cytokeratin-18 and the androgen receptor, and is androgen sensitive in vitro and in vivo. This cell line offers a cell-based model system of human prostate cancer. The cells are tumourigenic in SCID mice.
Species
Homo sapiens, human
Tissue of Origin
Prostate metastasis
Source
Prostate metastasis
Recommended Medium
Culture Properties
adherent
Morphology
epithelial
STR DNA Profile
Amelogenin: X,Y
CSF1PO: 10,12
D13S317: 11,12
D16S539: 9
D5S818: 12
D7S820: 9,12
THO1: 9.3
TPOX: 8,11
vWA: 18,19
Applications
It has been shown that VCaP prostate cancer cells produce the mouse xenotropic retrovirus Bxv-1, which was likely acquired by the cells during their xenotransplantation in mice.
Disease
Prostate carcinoma
Quality Control
Tests for mycoplasma, bacteria and fungi were negative
Storage and Shipping
liquid nitrogen vapor phase
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

For research use only. Not for any other purpose.

  • Q & A
  • Customer Review
Q:
What is the difference between TEM and scanning electron microscopy (SEM)?
A:

The main difference between TEM and SEM lies in the imaging technique. While TEM passes electrons through a thin specimen to create an image, SEM scans a focused beam of electrons across the surface of a specimen to generate a 3D image. TEM provides higher resolution for internal structure analysis, while SEM is better suited for surface imaging.

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Average Rating: 5.0    |    1 Scientist has reviewed this product

Reliable

As a cancer biologist, the tumor cells I purchase from Creative Bioarray maintain their genetic and phenotypic characteristics, allowing me to study key pathways and mechanisms associated with tumors.

13 Apr 2023


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