SUP-T11

Cat.No.: CSC-C0605

Species: Homo sapiens (Human)

Source: Bone Marrow

Morphology: small, polymorph cells growing singly in suspension

Culture Properties: suspension

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Cat.No.

CSC-C0605

Description

Derived from the bone marrow of a 74-year-old man with T-ALL at diagnosis; cell line was established in the presence of IGF-I under hypoxic conditions; cells were described to express high levels of TCL1A and TCL1B genes due to their juxtaposition from chromosome 14q32.1 to the regulatory element of the T-cell receptor C alpha/delta locus at chromosome 14q11

Species

Homo sapiens (Human)

Source

Bone Marrow

Recommended Medium

90% RPMI-1640 + 10% h.i. FBS

Culture Properties

suspension

Morphology

small, polymorph cells growing singly in suspension

Karyotype

Human highly rearranged hypodiploid karyotype with 5% polyploidy; 38(36-39)<2n>XX, -Y, -10, -13, -15, -16, -17, -21, -22, del(X)(q11?q23), add(X)(q23), der(1)del(1)(p32)t(1;4)(q32;q32.2), der(1)t(1;7)(q32;q32), der(2)t(2;4)(p23;p15 or q35), der(3)t(1;3)(p

Disease

Adult T Acute Lymphoblastic Leukemia

Quality Control

Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD2 +, CD3 +, CD4 -, CD5 +, CD6 +, CD7 +, CD8 -, CD13 -, CD19 -, CD20 -, CD34 -, HLA-DR -
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 5 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Synonyms

SupT11; SUPT11; SUPT-11; Stanford University Pediatric T-cell line 11

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

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For research use only. Not for any other purpose.