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SUP-T11
- Specification
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Cat.No.
CSC-C0605
Description
Derived from the bone marrow of a 74-year-old man with T-ALL at diagnosis; cell line was established in the presence of IGF-I under hypoxic conditions; cells were described to express high levels of TCL1A and TCL1B genes due to their juxtaposition from chromosome 14q32.1 to the regulatory element of the T-cell receptor C alpha/delta locus at chromosome 14q11
Species
Human
Source
T cell leukemia
Culture Properties
suspension
Morphology
small, polymorph cells growing singly in suspension
Karyotype
Human highly rearranged hypodiploid karyotype with 5% polyploidy; 38(36-39)<2n>XX, -Y, -10, -13, -15, -16, -17, -21, -22, del(X)(q11?q23), add(X)(q23), der(1)del(1)(p32)t(1;4)(q32;q32.2), der(1)t(1;7)(q32;q32), der(2)t(2;4)(p23;p15 or q35), der(3)t(1;3)(p
Quality Control
Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD2 +, CD3 +, CD4 -, CD5 +, CD6 +, CD7 +, CD8 -, CD13 -, CD19 -, CD20 -, CD34 -, HLA-DR -
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -
Immunology: CD2 +, CD3 +, CD4 -, CD5 +, CD6 +, CD7 +, CD8 -, CD13 -, CD19 -, CD20 -, CD34 -, HLA-DR -
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 5 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
Are there chromosomes in tumor cells?
A:
Solid tumors often contain many structural rearrangements involving multiple chromosomes and multiple breakpoints, and frequently cells from the same tumor contain different rearranged chromosomes, indicative of ongoing chromosome structure instability (CSI).
Average Rating: 5.0 | 1 Scientist has reviewed this product
Innovative research
This tumor cell product has allowed us to study cancer cells, leading to innovative research.
09 Mar 2023
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