The SUP-T1 established from the pleural effusion of an 8-year-old boy with T-lymphoblastic lymphoma in relapse. These cells are E-rosette, Leu 5, OKT9 and CALLA negative. They also express β2M, Leu 1, 2, 3a, 4, 6, 9 and OKT10 antigens and are CD4 positive. These cells are negative for Tac, HLA-DR and surface immunoglobulin.
Homo sapiens, human
STR DNA Profile
Amelogenin: X, X
vWA: 16, 18
92, XXYY, -2, -2, -9, -9, the following markers are present: 2inv(2*) (p21q11), +2inv(2*), del(2*)(Q21), 2del(4)(q31q35), 2del(5)(p13p14), 2del(6)(q23q27), 2inv(14)(q11q32), t(7;9)(q34;q34), der(9)t(7;9)
single, round cells in suspension
Tests for mycoplasma, bacteria and fungi were negative
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 4 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
The SUP-T1 cell line can be used for growth of HIV-1.
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