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KYO-1
- Specification
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Cat.No.
CSC-C0602
Description
Established from the peripheral blood of a 22-year-old Japanese man with chronic myeloid leukemia (CML) in myeloid blast crisis in 1981
Species
Human
Source
chronic myeloid leukemia in blast crisis
Culture Properties
suspension
Morphology
round cells growing singly or in clumps in suspension
Karyotype
Human flat-moded hypotetraploid karyotype; 83-90<4n>XX, -Y, -Y, +5, +8, -9, -9, +11, +11, +15, -16, -17, -17, -18, -18, +22, +22, +2mar; t(3;12)(p12.2;p11-12) x2, der(5)t(5;6)(p15;?q22)t(6;12)(q2?;?)ins(6;12)(q2?;?), del(6)(q22) x2, der(8)t(8;9)(q25;p11-1
Quality Control
Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD3 -, CD13 -, CD14 -, CD19 -, CD33 +, CD34 -, CD41 -, CD42b -, CD71 +, CD235a +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -
Immunology: CD3 -, CD13 -, CD14 -, CD19 -, CD33 +, CD34 -, CD41 -, CD42b -, CD71 +, CD235a +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 3 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
What type of cells can be used for karyotyping?
A:
Karyotype analysis is performed in cells undergoing cell division, or mitosis. Thus, only cells that are rapidly dividing (bone marrow or chorionic villus) or can be stimulated to divide in culture (peripheral blood lymphocytes, skin fibroblasts, and amniocytes) are used.
Average Rating: 4.0 | 1 Scientist has reviewed this product
Helpful
This product has allowed us to study the effects of different drugs on cancer cells, leading to potential new treatments.
01 Mar 2023
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