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GRANTA-452
- Specification
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Cat.No.
CSC-C0691
Description
Derived from a case of B cell acute lymphoblastic leukemia (B-ALL) following transformation from follicular B cell Non-Hodgkin lymphoma (B-NHL); described to carry a t(2;9) (p1;p13) and a t(9;14;18) (p13;q32;q21), to exhibit a biallelic deletion of CDKN2A as well as a BCL2 MBR rearrangement
Species
Human
Source
B cell leukemia
Culture Properties
suspension
Morphology
round cells growing singly in suspension
Karyotype
Human hyperdiploid karyotype with 5% polyploidy; 49(46-50)<2n>XXY, +X, +7, +11, der(1)t(1;7)(p36;p15), der(2)t(2;4)(p21;p15.2), der(3)t(1;3)(p26;q11), der(4)t(4;6)(p11;q22), del(6)(q13), trp(8)(q22q24), t(8;22)(q24;q11), der(9)t(2;9)(p13;p15.2), der(9)t(9
Quality Control
Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD3 -, CD10 +, CD13 -, CD19 +, CD20 -, CD34 -, CD37 +, CD38 +, cyCD79a +, CD80 +, HLA-DR +, sm/cyIgG +, sm/cyIgM -, sm/cykappa -, sm/cylambda +
Viruses: PCR: EBV -, HBV -, HCV -, HIV
Immunology: CD3 -, CD10 +, CD13 -, CD19 +, CD20 -, CD34 -, CD37 +, CD38 +, cyCD79a +, CD80 +, HLA-DR +, sm/cyIgG +, sm/cyIgM -, sm/cykappa -, sm/cylambda +
Viruses: PCR: EBV -, HBV -, HCV -, HIV
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 10 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
Can tumors revert to normal cells?
A:
The ability of a cancer cell to escape malignancy' and return to a normal state sounds like the work of Houdini: seemingly impossible. But like Houdini's daring feats, tumor reversion-when malignant cells regain control of their growth and simply stop behaving like cancer cells-is a very real thing.
Average Rating: 5.0 | 1 Scientist has reviewed this product
Impressed
I was impressed that the neat and secure packaging ensured the product's safety during shipping.
19 May 2022
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