Human iPSC-derived Osteoblasts

CSC-00839L

Osteoblasts synthesize collagen and express specialized proteins such as osteoclacin and osteopontin. As an organized group of connected cells, osteoblasts form part of the mineralized matrix. The matrix is part of the crucial skeletal support for humans. Mineralization is part of human's physiological homeostasis, such as acid-base balance, calcium or potassium maintenance. Human iPSC-derived Osteoblasts serve as a model system to examine bone mineralization, matrix formation for skeletal systems, bone remodeling, and bone metabolism. Human iPSC-derived Osteoblasts are reprogrammed using our proprietary serum-free, virus-free, nucleic-acids-free, feeder-free, and integration-free technology.. They expression biomarkers: Osteocalcin, COL1A1, FLT1, Bone Sialoprotein, RUNX2, and SPP1 (q/RT-PCR data not shown). Bone mineralization data (Alizarin S Red; 530nm absorbance data) are shown.

Human

For Research Use Only

Dry Ice

Sterility, Safety (BioSafety Level 2), HIV/viruses, bacteria, fungi: negative. Cell viability post-thawing (>92%)

Remove cryovials (dry ice packaging) and place the vial into liquid nitrogen for storage. Alternatively, thaw and use the cells immediately.

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