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Method for the diagnosis, prognosis and treatment of prostate cancer metastasis: U.S. Patent Application 14/050,262[P].

Method for the diagnosis, prognosis and treatment of prostate cancer metastasis: U.S. Patent Application 14/050,262[P]. Authors: Gomis R, Jean-Mairet J.
US 14/050,262

Abstract

The present invention relates to a method for the diagnosis or the prognosis ofmetastasis in prostate cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in prostate cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF expression level. Finally, the invention relates to the use of a c-MAF inhibitor as therapeutic target for treating the prostate cancer.