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Method for the diagnosis, prognosis and treatment of lung cancer metastasis: U.S. Patent Application 14/405,724[P].

Method for the diagnosis, prognosis and treatment of lung cancer metastasis: U.S. Patent Application 14/405,724[P]. Authors: Gomis R, Planet E.
PCT/IB2013/001859

Abstract

The present invention relates to a method for the diagnosis or the prognosis of metastasis in lung cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in lung cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF gene expression level. Finally, the invention relates to the use of a c-MAF inhibitor as therapeutic target for treating the lung cancer.