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Human Liver Microsomes-200 Donors
- Specification
- Recommended Products
Cat.No.
CSC-C4097X
Description
Creative Bioarray's Pooled Human Liver Microsomes provide a fully characterized, relevant, reliable and reproducible in vitro tool. Pooled of 200 donors give an accurate population representation and may be used to describe the metabolic profile of a drug or drug candidate in high-throughput assays as well as the following other uses:
Conduct studies of metabolic stability (% of original drug remaining over time)
Identify which cytochrome P450 (CYP) enzymes oxidize a drug candidate and which UDP-glucuronosyltransferase (UGT) enzymes are responsible for glucuronidation
Identify, quantify and characterize drug metabolites
Describe a drug's metabolic pathways
Identify inhibition of cytochrome P450 (CYP) enzymes
Conduct studies of metabolic stability (% of original drug remaining over time)
Identify which cytochrome P450 (CYP) enzymes oxidize a drug candidate and which UDP-glucuronosyltransferase (UGT) enzymes are responsible for glucuronidation
Identify, quantify and characterize drug metabolites
Describe a drug's metabolic pathways
Identify inhibition of cytochrome P450 (CYP) enzymes
Species
Human
Source
Liver
Storage and Shipping
Store in liquid nitrogen and ship in dry ice.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
Could you please verify the concentration of the stock HLMs?
A:
Concentration：20mg/ml
Q:
Do your company can also provide the pediatric liver microsomes, and not pooled adult HLMs?
A:
Yes, we also have pediatric liver microsomes from the single donor.
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