ActoFactor™ Human Tumor Necrosis Factor-alpha
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Cat.No.
CSC-CTK0312G
Description
Tumor Necrosis Factor alpha (TNF-α) is a pro-inflammatory cytokine that regulates immune responses, inflammation, and apoptosis. It is involved in the acute phase reaction and is a target for anti-inflammatory therapies.
Species
Human
Source
HEK293
GeneID
7124
Accession Number
P01375
Synonymous Name
TNF alpha, Tumor Necrosis Factor Alpha, TNFα, Cachectin
Molecular Mass
Approximately 17-20 kDa (reduced and non-reduced), a non-disulfide bonded homotrimeric glycosylated polypeptide chain.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. The specific activity of TNF alpha is minimally 7.00 x 10⁶ IU/mg and typically 1.59 x 10⁷ IU/mg.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA) of less than 0.2 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
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