ActoFactor™ Human Sonic Hedgehog
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Cat.No.
CSC-CTK0318G
Description
Sonic Hedgehog (Shh) is a morphogen crucial for embryonic patterning and tissue differentiation. It signals through Patched and Smoothened receptors, influencing cell fate decisions. Shh is involved in neural and hematopoietic stem cell regulation and is implicated in cancer development and tissue repair in adults.
Species
Human
Source
E. coli
GeneID
6469
Synonymous Name
Sonic Hedgehog, SHH, Vertebrate hedgehog homolog
Molecular Mass
Approximately 22 kDa (reduced and non-reduced) by SDS-PAGE.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. The ED50 is between 0.15 and 0.6 μg/mL, as measured by the ability to induce C3H10T1/2 cell differentiation in the presence of hBMP9 (20 ng/mL), evaluated through alkaline phosphatase production.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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