ActoFactor™ Human Neuregulin-1 β1/HRG1-β1 ECD Domain
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Cat.No.
CSC-CTK0328G
Description
Neuregulin-1 (NRG1) is a growth factor involved in neuronal development and survival. It binds to ErbB receptors, influencing pathways like PI3K/AKT. NRG1-β1 supports neuroprotection and attenuates inflammatory responses in ischemic conditions. Dysregulated NRG1 expression is linked to cancer progression and tissue remodeling.
Species
Human
Source
E. coli
GeneID
3084
Accession Number
AAA58639.1
Synonymous Name
NRG1-β1 / HRG1-β1 ECD domain, Neuregulin 1 Beta 1, Heregulin Beta 1, ARIA (Acetylcholine Receptor-Inducing Activity)
Molecular Mass
The DTT-reduced and non-reduced protein migrate at approximately 33 kD by SDS-PAGE.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. The ED50 for the evaluated agent is between 1 and 5 ng/mL, as determined by the induction of MCF-7 cell proliferation
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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