ActoFactor™ Human Leukemia Inhibitory Factor (E. coli)
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Cat.No.
CSC-CTK0335G
Description
LIF is a cytokine that supports stem cell self-renewal and differentiation. It signals through the gp130 receptor complex, influencing pathways like STAT3. LIF is involved in hematopoiesis, neuronal differentiation, and immune tolerance. Elevated LIF levels are associated with inflammatory conditions and tissue repair.
Species
Human
Source
E. coli
GeneID
3976
Synonymous Name
LIF, Leukemia Inhibitory Factor, HILDA (Human Interleukin for DA cells)
Molecular Mass
Approximately 20 kDa in DTT-reducing conditions and 18 kDa in non-reducing condition by SDS-PAGE.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. Human LIF induces proliferation of TF-1 cells in a dose-dependent manner, with an ED50 between 0.03 and 0.12 ng/mL, the specific activity is ≥ 1.4 x 10⁷ IU/mg.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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