IL-7 is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells, but is not produced by normal lymphocytes
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Approximately 17.4 kDa, a single non-glycosylated polypeptide chain containing 152 amino acids
5μg, 100μg, 500μg, 1000μg
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine 2E8 cells is less than 0.5 ng/ml, corresponding to a specific activity of > 2.0 ×106 IU/mg.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Store lyophilized cytokine at -20°C to -80°C.
Avoid repeated freeze/thaw cycles.
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