ActoFactor™ Human Interleukin 34 (CHO)
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Cat.No.
CSC-CTK0345G
Description
IL-34 shares structural similarities with M-CSF and binds to the CSF-1 receptor, supporting macrophage and dendritic cell functions. It is involved in immune regulation and tissue homeostasis. Elevated IL-34 levels are associated with conditions like polycystic ovary syndrome and acute ischemic stroke.
Species
Human
Source
CHO
GeneID
146433
Accession Number
Q6ZMJ4-1
Synonymous Name
IL-34, Interleukin 34
Molecular Mass
Approximately 38 kDa (reduced), 36 and 68 kDa (non-reduced), a homodimeric glycosylated polypeptide chain.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. Human IL-34 induces MCP-1 (CCL2) production in human peripheral blood mononuclear cells (PBMC) in a dose-dependent manner, with an ED50 ranging from 4 to 20 ng/mL.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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