ActoFactor™ Human Interleukin 21 (HEK293)
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- Q & A
- Customer Review
Cat.No.
CSC-CTK0350G
Description
IL-21 is a type I, 4-α-helix bundle cytokine primarily produced by CD4+ T cells and NK cells, which enhances the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. It plays a role in immune regulation and has potential therapeutic applications in cancer immunotherapy.
Species
Human
Source
HEK293
GeneID
59067
Accession Number
Q9HBE4
N-terminal Sequence
Met-Glu-Glu-Val-Ser-Glu-Try-(Cys)-Ser-His
Synonymous Name
IL-21, Interleukin 21
Molecular Mass
Approximately 18 kDa (reduced) and 17 kDa (non-reduced), a monomeric glycosylated polypeptide chain.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. The ED50 for IL-21, as measured in a cell proliferation assay using B9 mouse hybridoma cells, is between 5.00 and 50.0 ng/mL, corresponding to a specific activity of > 1.00 x 10⁶ units/mg.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA) of less than 0.2 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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