ActoFactor™ Human Interleukin 10 (HEK293)
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Cat.No.
CSC-CTK0358G
Description
Interleukin 10 (IL-10) is an anti-inflammatory cytokine that inhibits the production of pro-inflammatory cytokines and enhances the function of regulatory T cells. It plays a crucial role in limiting excessive immune responses and maintaining immune homeostasis.
Species
Human
Source
HEK293
GeneID
3586
Accession Number
P22301
N-terminal Sequence
Amino acid sequencing of the alpha chain was blocked, suggesting it is consistent with Gln32
Gln32-Arg-Lys-Arg-Arg-Asn-Thr-Ile-His-Glu ( alpha-chain)
Val495-Val-Asn-Gly-Ile-Pro-Thr-Arg-Thr-Asn ( beta-chain)
Synonymous Name
IL-10, Interleukin 10, Cytokine Synthesis Inhibitory Factor (CSIF)
Molecular Mass
Approximately 18 kDa (reduced) and 37 kDa (non-reduced), a homodimeric glycosylated polypeptide chain.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. The specific activity of IL-1 alpha is minimally 1.00 x 10⁷ IU/mg and typically 3.16 x 10⁷ IU/mg.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA) of less than 0.2 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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