ActoFactor™ Human Growth Differentiation Factor 8 (Myostatin)
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Cat.No.
CSC-CTK0374G
Description
Growth Differentiation Factor 8, also known as Myostatin, is a member of the TGF-β superfamily that negatively regulates muscle growth. Inhibiting myostatin can lead to increased muscle mass, making it a target for therapies aimed at treating muscle wasting diseases.
Species
Human
Source
NSO
GeneID
266078
Accession Number
O08689.1
Synonymous Name
GDF-8 / Myostatin, Growth Differentiation Factor 8, MSTN
Molecular Mass
Approximately 12.4 kDa, a single non-glycosylated polypeptide chain.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. The ED₅₀, as determined by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells, is 2 - 10 ng/mL.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile water containing 0.1% endotoxin-free recombinant human serum albumin (HSA) to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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